Compound Q&A

How is 2-Thiophenesulfonyl chloride (CAS: 16629-19-9) typically synthesized?

Answer

2-Thiophenesulfonyl chloride
2-Thiophenesulfonyl chloride is typically synthesized by the chlorosulfonylation of thiophene using thionyl chloride as the reagent. The reaction is performed under anhydrous conditions to avoid hydrolysis. Catalysts such as aluminum chloride or aluminum bromide may be used to improve the yield and selectivity of the product.

About

CAS No 16629-19-9
English Name 2-Thiophenesulfonyl chloride
Molecular Formula C4H3ClO2S2
Molecular Weight 182.65 g/mol
SMILES C1=CSC(=C1)S(=O)(=O)Cl
InChIKey VNNLHYZDXIBHKZ-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09

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