Compound Q&A

How is Androst-4-ene-3,11,17-trione (CAS: 382-45-6) typically synthesized?

Answer

Androst-4-ene-3,11,17-trione
Androst-4-ene-3,11,17-trione can be synthesized via various routes. One common method involves the reduction of androst-4-en-3-one to androst-4-ene, followed by a Claisen condensation with acetone to form the trione. The synthesis typically uses sodium borohydride for the reduction step and an appropriate base like sodium hydroxide for the condensation. The yield and selectivity are influenced by the conditions used.

About

CAS No 382-45-6
English Name Androst-4-ene-3,11,17-trione
Molecular Formula C19H24O3
Molecular Weight 300.4 g/mol
SMILES CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4=O)C
InChIKey RZRPTBIGEANTGU-IRIMSJTPSA-N
Last Updated: 2025-09-26 00:09

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