Compound Q&A
How is (6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (CAS: 187235-37-6) typically synthesized?
Answer
![(6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine](https://static.chemtradehub.com/structs/187/187235-37-6-5456.webp "(6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine")
(6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine can be synthesized via a multi-step process involving the protection of the imidazole ring, introduction of the nitro and trifluoromethoxy groups, followed by deprotection and ring closure. Commonly used catalysts include acid catalysts such as trifluoroacetic acid, and the process typically yields the desired product with good selectivity.
About
CAS No
187235-37-6
English Name
(6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
Molecular Formula
C14H12F3N3O5
Molecular Weight
359.26 g/mol
SMILES
[O-][N+](=O)c1cn2c(n1)OC[C@H](C2)OCc1ccc(cc1)OC(F)(F)F
InChIKey
ZLHZLMOSPGACSZ-NSHDSACASA-N
Last Updated: 2025-09-26 00:09
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