Compound Q&A
How is 2-(Chloromethyl)tetrahydrofuran (CAS: 3003-84-7) typically synthesized?
Answer
2-(Chloromethyl)tetrahydrofuran is usually synthesized through the reaction of 1,4-dioxane with chloroform in the presence of a base. The reaction proceeds through an SN2 mechanism, yielding a high yield of the desired product. Sodium hydride is often used as a base in this synthesis.
About
CAS No
3003-84-7
English Name
2-(Chloromethyl)tetrahydrofuran
Molecular Formula
C5H9ClO
Molecular Weight
120.58 g/mol
SMILES
C1CC(OC1)CCl
InChIKey
IVJLGIMHHWKRAN-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09
