Compound Q&A
How is 3'-O-Methylguanosine (CAS: 10300-27-3) typically synthesized?
Answer
3'-O-Methylguanosine is typically synthesized by methylation of guanosine using dimethyl sulfate or similar methylating agents. The reaction is catalyzed by anhydrous conditions and is carried out with high selectivity, yielding a high purity product. The overall yield is around 80-90%.
About
CAS No
10300-27-3
English Name
3'-O-Methylguanosine
Molecular Formula
C11H15N5O5
Molecular Weight
297.27 g/mol
SMILES
COC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)CO
InChIKey
UYARPHAXAJAZLU-KQYNXXCUSA-N
Last Updated: 2025-09-26 00:09
