Compound Q&A

How is 2-(3-Bromopropyl)-1H-isoindole-1,3(2H)-dione (CAS: 5460-29-7) typically synthesized?

Answer

2-(3-Bromopropyl)-1H-isoindole-1,3(2H)-dione
2-(3-Bromopropyl)-1H-isoindole-1,3(2H)-dione (CAS: 5460-29-7) is typically synthesized via a multi-step process, involving the bromination of propyl isonitrile and subsequent reaction with isoindole. The synthesis often uses a Lewis acid catalyst such as aluminum chloride. The yield is around 70-80%, and the reaction is highly selective for the bromo substitution on the propyl group.

About

CAS No 5460-29-7
English Name 2-(3-Bromopropyl)-1H-isoindole-1,3(2H)-dione
Molecular Formula C11H10BrNO2
Molecular Weight 268.11 g/mol
SMILES C1=CC=C2C(=C1)C(=O)N(C2=O)CCCBr
InChIKey VKJCJJYNVIYVQR-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09

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