How is 2-(4-aminophenyl)-1,1,1,3,3,3-hexafluoro-propan-2-ol (CAS: 722-92-9) typically synthesized?

2-(4-aminophenyl)-1,1,1,3,3,3-hexafluoro-propan-2-ol is synthesized via a multistep process involving the reaction of 4-hydroxybenzaldehyde with hexafluoroacetone followed by reduction and amidation. Commonly, this involves catalytic reduction using palladium or rhodium catalysts under hydrogen atmosphere and subsequent amidation with an amine reagent. The overall yield of the product can be up to 85%. The reaction is selective and provides high purity products.