Compound Q&A

How is 1-(3-Methylphenyl)-1-propanone (CAS: 51772-30-6) typically synthesized?

Answer

1-(3-Methylphenyl)-1-propanone
1-(3-Methylphenyl)-1-propanone can be synthesized through a Wittig reaction of 3-methylbenzyl alcohol with triphenylphosphine and acrylonitrile. The reaction is performed in the presence of a Lewis acid catalyst, such as aluminum trichloride, to improve yield and selectivity. The process typically yields 85-90% of the desired product.

About

CAS No 51772-30-6
English Name 1-(3-Methylphenyl)-1-propanone
Molecular Formula C10H12O
Molecular Weight 148.20499999999998 g/mol
SMILES CCC(=O)c1cccc(C)c1
InChIKey QHVNQIJBHWOZRJ-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48

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