Compound Q&A
How is 5-Chloro-1,3-dihydro-2H-indol-2-one (CAS: 17630-75-0) typically synthesized?
Answer
5-Chloro-1,3-dihydro-2H-indol-2-one can be synthesized via a multi-step process. Common methods include the condensation of chloroacetic acid with indole followed by cyclization. This process typically requires the use of Lewis acids as catalysts and can achieve a yield of around 70-80%. Selectivity towards the desired product can be enhanced by careful control of reaction conditions.
About
CAS No
17630-75-0
English Name
5-Chloro-1,3-dihydro-2H-indol-2-one
Molecular Formula
C8H6ClNO
Molecular Weight
167.59 g/mol
SMILES
C1C2=C(C=CC(=C2)Cl)NC1=O
InChIKey
WWJLCYHYLZZXBE-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
