Compound Q&A
How is 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine (CAS: 827614-64-2) typically synthesized?
Answer
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine can be synthesized by the reaction of 2-pyridinamine with 1,1,1,3,3,3-hexafluoro-2-propanol in the presence of a base like cesium carbonate. The reaction is typically carried out in DMF at room temperature. The product is isolated by filtration and can be further purified by recrystallization or column chromatography.
About
CAS No
827614-64-2
English Name
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine
Molecular Formula
C11H17BN2O2
Molecular Weight
220.08 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CN=C(C=C2)N
InChIKey
YFTAUNOLAHRUIE-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
