Compound Q&A
How is Methyl 5-chloro-2-nitrobenzoate (CAS: 51282-49-6) typically synthesized?
Answer
Methyl 5-chloro-2-nitrobenzoate is typically synthesized via the nitration of methyl 2-chlorobenzoate using concentrated nitric acid and sulfuric acid as a catalyst. The reaction is carried out under reflux conditions to ensure complete nitration. The product is then purified by recrystallization from an appropriate solvent. This method provides a yield of around 80-85%.
About
CAS No
51282-49-6
English Name
Methyl 5-chloro-2-nitrobenzoate
Molecular Formula
C8H6ClNO4
Molecular Weight
215.59 g/mol
SMILES
COC(=O)C1=C(C=CC(=C1)Cl)[N+](=O)[O-]
InChIKey
JGBJHRKCUKTQOE-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
