Compound Q&A
How is Ethyl 2-oxo-4-phenylbutyrate (CAS: 64920-29-2) typically synthesized?
Answer
Ethyl 2-oxo-4-phenylbutyrate (CAS: 64920-29-2) is typically synthesized via a multistep process, starting with phenylacetic acid and acetic anhydride. A suitable catalyst, such as p-toluenesulfonic acid, is used to facilitate the esterification reaction. The crude product is then purified using column chromatography or recrystallization. Yield can reach up to 85% with good selectivity.
About
CAS No
64920-29-2
English Name
Ethyl 2-oxo-4-phenylbutyrate (>90%)
Molecular Formula
C12H14O3
Molecular Weight
206.24 g/mol
SMILES
CCOC(=O)C(=O)CCC1=CC=CC=C1
InChIKey
STPXIOGYOLJXMZ-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
