Compound Q&A

How is (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate (CAS: 328086-60-8) typically synthesized?

Answer

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate
(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate is usually synthesized by reacting 3-(S)-2-oxopyrrolidin-1-yl)propan-2-one with (S)-2-aminotetrahydropyranyl N-tert-butoxycarbonylamine in the presence of a suitable base. The reaction yields a high level of purity and selectivity, with a typical yield of 70-80%.

About

English Name (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate
Molecular Formula C13H22N2O5
Molecular Weight 286.33 g/mol
SMILES CC(C)(C)OC(=O)NC(CC1CCNC1=O)C(=O)OC
InChIKey HTQMBOWAEPNWLI-IUCAKERBSA-N
Last Updated: 2025-09-23 10:23

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