(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate(CAS: 328086-60-8)

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate is a white crystalline solid with a molecular weight of approximately 327.44 g/mol. It has a melting point of around 110-112°C and is sparingly soluble in water but more soluble in organic solvents like dichloromethane and ethanol. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution and ester hydrolysis.

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate is usually synthesized by reacting 3-(S)-2-oxopyrrolidin-1-yl)propan-2-one with (S)-2-aminotetrahydropyranyl N-tert-butoxycarbonylamine in the presence of a suitable base. The reaction yields a high level of purity and selectivity, with a typical yield of 70-80%.

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate is primarily used in the pharmaceutical and organic synthesis industries. It serves as a valuable intermediate in the preparation of various biologically active compounds and is also utilized in polymer synthesis and sensor applications.

When handling (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a dry, cool place away from heat and direct sunlight. In case of a spill, use appropriate spill cleanup procedures and refer to the Safety Data Sheet (SDS) for detailed instructions. Always work in a well-ventilated area or a fume hood to minimize inhalation risk.