Compound Q&A
How is 4-Fluoro-2-methylaniline (CAS: 452-71-1) typically synthesized?
Answer
4-Fluoro-2-methylaniline (CAS: 452-71-1) is typically synthesized by the reaction of 2-methylaniline with hydrogen fluoride. This process involves the nucleophilic substitution of the amino group by a fluoride ion. The reaction is carried out at low temperatures, and the product is isolated by recrystallization. This method provides a yield of up to 85%.
About
CAS No
452-71-1
English Name
4-Fluoro-2-methylaniline
Molecular Formula
C7H8FN
Molecular Weight
125.15 g/mol
SMILES
CC1=C(C=CC(=C1)F)N
InChIKey
KMHLGVTVACLEJE-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
