Compound Q&A
How is 3-[(3R)-3-{[(4-Fluorophenyl)sulfonyl]amino}-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid (CAS: 116649-85-5) typically synthesized?
Answer
![3-[(3R)-3-{[(4-Fluorophenyl)sulfonyl]amino}-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid](https://static.chemtradehub.com/structs/116/116649-85-5-c571.webp "3-[(3R)-3-{[(4-Fluorophenyl)sulfonyl]amino}-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid")
The compound is synthesized through a multi-step process involving the condensation of a sulfonyl chloride with a carbazol derivative, followed by amination. The reaction is catalyzed by a Lewis acid and proceeds with good selectivity and yield, making it a reliable method for industrial production.
About
CAS No
116649-85-5
English Name
3-[(3R)-3-{[(4-Fluorophenyl)sulfonyl]amino}-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid
Molecular Formula
C21H21FN2O4S
Molecular Weight
416.47 g/mol
SMILES
C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O
InChIKey
LDXDSHIEDAPSSA-OAHLLOKOSA-N
Last Updated: 2025-09-23 10:23
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