Compound Q&A
How is Naltrexone HCl (CAS: 16676-29-2) typically synthesized?
Answer
Naltrexone HCl is typically synthesized via a multi-step process involving the conversion of naltrexone to its hydrochloride salt. Common methods include the reaction of naltrexone with hydrochloric acid under controlled conditions. This synthesis is highly selective and yields up to 95% of the product. The process requires careful control of pH and temperature to ensure high purity and yield.
About
CAS No
16676-29-2
English Name
Naltrexone HCl
Molecular Formula
C20H24ClNO4
Molecular Weight
377.87 g/mol
SMILES
Cl.Oc1ccc2C[C@H]3N(CC4CC4)CC[C@]5([C@H]6Oc1c25)[C@@]3(O)CCC6=O
InChIKey
RHBRMCOKKKZVRY-ITLPAZOVSA-N
Last Updated: 2025-09-23 10:23
