Compound Q&A

How is (2S)-2-Hydroxy-4-methylpentanoic acid (CAS: 13748-90-8) typically synthesized?

Answer

(2S)-2-Hydroxy-4-methylpentanoic acid
(2S)-2-Hydroxy-4-methylpentanoic acid can be synthesized from 4-methylpentanoyl chloride and sodium hydroxide in an aqueous medium. The reaction proceeds with high selectivity to the (2S) configuration. The yield is typically around 75-85%, and the product can be isolated by recrystallization from water or methanol.

About

CAS No 13748-90-8
English Name (2S)-2-Hydroxy-4-methylpentanoic acid
Molecular Formula C6H12O3
Molecular Weight 132.16 g/mol
SMILES CC(C)C[C@H](O)C(=O)O
InChIKey LVRFTAZAXQPQHI-YFKPBYRVSA-N
Last Updated: 2025-09-23 10:23

Related Q&A

Compound Q&A

What are the physical and chemical properties of (2S)-2-Hydroxy-4-methylpentanoic acid (CAS: 13748-90-8)?

(2S)-2-Hydroxy-4-methylpentanoic acid is a colorless crystalline solid with a molecular weight of ap...

Compound Q&A

What industries use (2S)-2-Hydroxy-4-methylpentanoic acid (CAS: 13748-90-8)?

(2S)-2-Hydroxy-4-methylpentanoic acid finds applications in the pharmaceutical industry as a precurs...

Compound Q&A

What precautions should be taken when handling (2S)-2-Hydroxy-4-methylpentanoic acid (CAS: 13748-90-8)?

When handling (2S)-2-Hydroxy-4-methylpentanoic acid, it is essential to wear appropriate personal pr...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...