Compound Q&A
How is (2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide (CAS: 863127-76-8) typically synthesized?
Answer
(2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide can be synthesized via a condensation reaction between 2-chloro-6-methylacetophenone and ethoxyacryloyl chloride in the presence of a base such as triethylamine. The reaction yield is typically around 75-85%, and the process involves a key step of selective acylation to form the desired product.
About
CAS No
863127-76-8
English Name
(2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide
Molecular Formula
C12H14ClNO2
Molecular Weight
239.7 g/mol
SMILES
CCO/C=C/C(=O)Nc1c(C)cccc1Cl
InChIKey
DBYFNZJHXGNAGW-BQYQJAHWSA-N
Last Updated: 2025-09-22 19:21
