Compound Q&A

How is 2-Amino-4-pyrimidinol (CAS: 108-53-2) typically synthesized?

Answer

2-Amino-4-pyrimidinol
2-Amino-4-pyrimidinol can be synthesized via the Mannich reaction of 4-formamidopyrimidine with formaldehyde and a base like sodium hydroxide. The yield is typically around 70-80%, and it is important to use appropriate catalysts and control the reaction conditions to achieve high selectivity.

About

CAS No 108-53-2
English Name 2-Amino-4-pyrimidinol
Molecular Formula C4H5N3O
Molecular Weight 111.1 g/mol
SMILES C1=CN=C(NC1=O)N
InChIKey XQCZBXHVTFVIFE-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21

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