2-Amino-4-pyrimidinol(CAS: 108-53-2)

2-Amino-4-pyrimidinol is a colorless or white crystalline solid with a molecular weight of 121.14 g/mol. It is slightly soluble in water and soluble in methanol. The compound is known for its basic nature and can react with acids to form salts. It is also reactive towards nucleophiles and can undergo substitution reactions.

2-Amino-4-pyrimidinol can be synthesized via the Mannich reaction of 4-formamidopyrimidine with formaldehyde and a base like sodium hydroxide. The yield is typically around 70-80%, and it is important to use appropriate catalysts and control the reaction conditions to achieve high selectivity.

2-Amino-4-pyrimidinol is used in the pharmaceutical industry as an intermediate for drug synthesis. It also finds applications in polymer chemistry for the preparation of functional polymers, and in the development of chemical sensors and semiconductors due to its unique properties.

When handling 2-Amino-4-pyrimidinol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up carefully using appropriate absorbents, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed safety information.