Compound Q&A
How is 1-(4-Fluorophenyl)piperazine (CAS: 2252-63-3) typically synthesized?
Answer
1-(4-Fluorophenyl)piperazine (CAS: 2252-63-3) is typically synthesized via multistep organic reactions starting from 4-fluorophenol and piperazine. The synthesis involves protecting groups, coupling reactions, and deprotection steps. Commonly used catalysts and reagents include sodium hydroxide, dichloromethane, and pyridine. The overall yield is around 50-60%.
About
CAS No
2252-63-3
English Name
1-(4-Fluorophenyl)piperazine
Molecular Formula
C10H13FN2
Molecular Weight
180.23 g/mol
SMILES
C1CN(CCN1)C2=CC=C(C=C2)F
InChIKey
AVJKDKWRVSSJPK-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21
