Compound Q&A

Are there alternatives to N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide (CAS: 77377-52-7) in synthesis?

Answer

N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide
For syntheses requiring similar functionality, alternatives such as trifluoroacetic anhydride or other trifluoroacetamide derivatives can be considered. These alternatives may offer comparable reactivity but with different reaction profiles and handling requirements.

About

CAS No 77377-52-7
English Name N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide
Molecular Formula C9H18F3NOSi
Molecular Weight 241.33 g/mol
SMILES CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
InChIKey QRKUHYFDBWGLHJ-UHFFFAOYSA-N
Last Updated: 2025-09-20 20:46

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