Compound Q&A
How is N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide (CAS: 144222-34-4) typically synthesized?
Answer
![N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide](https://static.chemtradehub.com/structs/144/144222-34-4-12b9.webp "N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide")
N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide is synthesized via multi-step organic synthesis involving the preparation of the amino-substituted phenyl ethylamine followed by sulfonamide formation with 4-methylbenzenesulfonyl chloride. The reaction typically requires a phase-transfer catalyst and is carried out under mild conditions to achieve high yield and selectivity.
About
CAS No
144222-34-4
English Name
N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide
Molecular Formula
C21H22N2O2S
Molecular Weight
366.49 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(C2=CC=CC=C2)C(C3=CC=CC=C3)N
InChIKey
UOPFIWYXBIHPIP-NHCUHLMSSA-N
Last Updated: 2025-09-19 21:14
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