Compound Q&A
How is 6-Fluoronicotinic acid (CAS: 403-45-2) typically synthesized?
Answer
6-Fluoronicotinic acid is typically synthesized by fluorination of nicotinic acid using reagents like sulfuryl fluoride or trifluoroacetic anhydride. The process involves selective fluorination under controlled conditions, with yields ranging from 70% to 90% depending on the method and purity of starting materials.
About
CAS No
403-45-2
English Name
6-Fluoronicotinic acid
Molecular Formula
C6H4FNO2
Molecular Weight
141.101 g/mol
SMILES
C1=CC(=NC=C1C(=O)O)F
InChIKey
UJDLCTNVHJEBDG-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14
