Compound Q&A
How is Ethyl (4-nitrophenyl)acetate (CAS: 5445-26-1) typically synthesized?
Answer
Ethyl (4-nitrophenyl)acetate (CAS: 5445-26-1) is typically synthesized by the esterification of 4-nitrophenol with acetic anhydride in the presence of a strong acid catalyst like sulfuric acid. The reaction is carried out at elevated temperatures to achieve high yield and selectivity. This compound can also be prepared by other methods, such as direct nitration of ethyl phenylacetate, followed by purification.
About
CAS No
5445-26-1
English Name
Ethyl (4-nitrophenyl)acetate
Molecular Formula
C10H11NO4
Molecular Weight
209.2 g/mol
SMILES
CCOC(=O)CC1=CC=C(C=C1)[N+](=O)[O-]
InChIKey
DWDRNKYLWMKWTH-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14
