Compound Q&A

How is (2S,3R)-2-{[(benzyloxy)carbonyl]amino}-3-hydroxybutanoic acid (CAS: 19728-63-3) typically synthesized?

Answer

(2S,3R)-2-{[(benzyloxy)carbonyl]amino}-3-hydroxybutanoic acid
(2S,3R)-2-{[(Benzyloxy)carbonyl]amino}-3-hydroxybutanoic acid can be synthesized via a multi-step process involving the protection of the amino group, followed by amidation and subsequent deprotection. Common starting materials include benzyloxycarbonyl chloride and 3-amino-2-hydroxybutanoic acid. The reaction typically involves the use of triethylamine as a base and is conducted under mild conditions to achieve high yield and selectivity.

About

CAS No 19728-63-3
English Name (2S,3R)-2-{[(benzyloxy)carbonyl]amino}-3-hydroxybutanoic acid
Molecular Formula C12H15NO5
Molecular Weight 253.254 g/mol
SMILES CC(C(C(=O)O)NC(=O)OCC1=CC=CC=C1)O
InChIKey IPJUIRDNBFZGQN-SCZZXKLOSA-N
Last Updated: 2025-09-19 21:14

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