Compound Q&A
How is Cosyntropin (CAS: 16960-16-0) typically synthesized?
Answer
Cosyntropin is synthesized through a multi-step chemical process involving amino acid coupling and acylation. The key steps include the coupling of amino acids to form the peptide backbone, followed by side-chain modifications. The synthesis typically involves the use of coupling reagents like HATU or EDC, and the reaction is carried out in organic solvents like DMF. The yield is usually between 60-80%, and the product is purified by HPLC or chromatography.
About
CAS No
16960-16-0
English Name
Cosyntropin
Molecular Formula
C136H210N40O31S
Molecular Weight
2933.4 g/mol
SMILES
CC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)O)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC8=CNC=N8)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC9=CC=C(C=C9)O)NC(=O)C(CO)N
InChIKey
ZOEFCCMDUURGSE-SQKVDDBVSA-N
Last Updated: 2025-09-16 13:49
