Compound Q&A
How is [3-(Trifluoromethyl)phenyl]acetic acid (CAS: 351-35-9) typically synthesized?
Answer
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Common synthesis methods for [3-(Trifluoromethyl)phenyl]acetic acid involve the reaction of 3-(trifluoromethyl)benzaldehyde with acetic anhydride in the presence of a suitable catalyst, such as thionyl chloride or acetic acid. This process yields the desired product with good selectivity and moderate to high yield. The exact conditions vary depending on the specific catalyst and reaction conditions used.
About
CAS No
351-35-9
English Name
[3-(Trifluoromethyl)phenyl]acetic acid
Molecular Formula
C9H7F3O2
Molecular Weight
204.15 g/mol
SMILES
C1=CC(=CC(=C1)C(F)(F)F)CC(=O)O
InChIKey
BLXXCCIBGGBDHI-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49
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