Compound Q&A

How is Betahistine mesylate (CAS: 54856-23-4) typically synthesized?

Answer

Betahistine mesylate
Betahistine mesylate is synthesized through an acylation reaction of betahistine with methanesulfonyl chloride. The reaction is typically performed in the presence of a base such as triethylamine. The product is then purified by recrystallization. This method provides good selectivity and yields up to 95%.

About

CAS No 54856-23-4
English Name Betahistine mesylate
Molecular Formula C10H20N2O6S2
Molecular Weight 232.31 g/mol
SMILES CNCCC1=CC=CC=N1.CS(=O)(=O)O.CS(=O)(=O)O
InChIKey FUWLKZQYMWTFBA-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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