Compound Q&A

How is 5-Bromo-3-fluoro-2-pyridinamine (CAS: 748812-37-5) typically synthesized?

Answer

5-Bromo-3-fluoro-2-pyridinamine
5-Bromo-3-fluoro-2-pyridinamine is synthesized through a multistep process involving the bromination and fluorination of 2-pyridinamine. Commonly, this involves the use of N-bromosuccinimide (NBS) as a brominating agent and fluoroform as a fluorinating agent. The reaction is typically carried out in the presence of an appropriate solvent, and the product is purified using recrystallization or column chromatography.

About

English Name 5-Bromo-3-fluoro-2-pyridinamine
Molecular Formula C5H4BrFN2
Molecular Weight 191.003 g/mol
SMILES C1=C(C=NC(=C1F)N)Br
InChIKey QLXASFJHUCKEHU-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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