Compound Q&A

How is Urapidil hydrochloride (CAS: 64887-14-5) typically synthesized?

Answer

Urapidil hydrochloride
Urapidil hydrochloride is synthesized by a multi-step process starting from 2-(2-aminoethyl)-1,3-propanediol. The key steps include amide formation, hydrochloride salt formation, and crystallization. The synthesis involves the use of acetic anhydride, hydrochloric acid, and other reagents. The yield is typically around 85% with good selectivity.

About

CAS No 64887-14-5
English Name Urapidil hydrochloride
Molecular Formula C20H30ClN5O3
Molecular Weight 423.95 g/mol
SMILES CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl
InChIKey KTMLZVUAXJERAT-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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