Compound Q&A

How is hexyl salicylate (CAS: 6259-76-3) typically synthesized?

Answer

Hexyl salicylate
Hexyl salicylate is typically synthesized through the esterification of salicylic acid with hexanol in the presence of a strong acid catalyst like sulfuric acid. The process involves refluxing the mixture and then neutralizing the acid with a base to precipitate the product. The yield is generally around 85-90%, with good selectivity towards the desired ester.

About

CAS No 6259-76-3
English Name Hexyl salicylate
Molecular Formula C13H18O3
Molecular Weight 222.28 g/mol
SMILES CCCCCCOC(=O)c1ccccc1O
InChIKey DUKPKQFHJQGTGU-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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