Compound Q&A

How is (8alpha,9R,8'''alpha,9'''R)-9,9'-[1,4-Phthalazinediylbis(oxy)]bis(6'-methoxy-10,11-dihydrocinchonan) (CAS: 140924-50-1) typically synthesized?

Answer

(8alpha,9R,8'''alpha,9'''R)-9,9'-[1,4-Phthalazinediylbis(oxy)]bis(6'-methoxy-10,11-dihydrocinchonan)
The compound is synthesized through a multi-step process involving the formation of a phthalazinediyl bis(ether) intermediate. The key steps include the introduction of methoxy groups and the formation of the phthalazinediyl linkage. Specific conditions such as temperature, pressure, and the use of catalysts like titanium tetrachloride are crucial for achieving high selectivity and yield.

About

English Name (8alpha,9R,8'''alpha,9'''R)-9,9'-[1,4-Phthalazinediylbis(oxy)]bis(6'-methoxy-10,11-dihydrocinchonan)
Molecular Formula C48H54N6O4
Molecular Weight 779 g/mol
SMILES CCC1CN2CCC1CC2C(C3=C4C=C(C=CC4=NC=C3)OC)OC5=NN=C(C6=CC=CC=C65)OC(C7CC8CCN7CC8CC)C9=C1C=C(C=CC1=NC=C9)OC
InChIKey YUCBLVFHJWOYDN-PDNPBWJSSA-N
Last Updated: 2025-09-13 09:53

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