Compound Q&A
How is Methyl 6-aminonicotinate (CAS: 36052-24-1) typically synthesized?
Answer
Methyl 6-aminonicotinate is typically synthesized by the reaction of methyl 6-chloronicotinate with sodium hydride, followed by the addition of an amine. This process involves the displacement of the chloride group with an amine, yielding the desired product with high selectivity and good yield. The reaction is usually carried out in an inert solvent like dimethylformamide (DMF).
About
CAS No
36052-24-1
English Name
Methyl 6-aminonicotinate
Molecular Formula
C7H8N2O2
Molecular Weight
152.15 g/mol
SMILES
COC(=O)C1=CN=C(C=C1)N
InChIKey
JACPDLJUQLKABC-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15
