Compound Q&A
How is Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate (CAS: 154477-54-0) typically synthesized?
Answer
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Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate is synthesized through the condensation of 4-(4-chlorobutanoyl)phenol with methyl 2-methylpropanoate in the presence of a mild base like potassium carbonate. The reaction yields the desired compound in good yield with high selectivity. The process is often carried out in a solvent such as dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).
About
CAS No
154477-54-0
English Name
Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate
Molecular Formula
C15H19ClO3
Molecular Weight
282.77 g/mol
SMILES
CC(C)(C1=CC=C(C=C1)C(=O)CCCCl)C(=O)OC
InChIKey
ULWORPZJUIFPIC-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15
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