Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate(CAS: 154477-54-0)

Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate has a crystalline form with a molecular weight of approximately 332.22 g/mol. It is sparingly soluble in water but readily soluble in organic solvents such as methanol and acetone. Chemically, it is relatively stable but can undergo hydrolysis under basic conditions. It reacts with strong acids and bases to form their respective salts.

Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate is synthesized through the condensation of 4-(4-chlorobutanoyl)phenol with methyl 2-methylpropanoate in the presence of a mild base like potassium carbonate. The reaction yields the desired compound in good yield with high selectivity. The process is often carried out in a solvent such as dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).

Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate is used in the pharmaceutical industry for the synthesis of certain organic compounds and intermediates. It may also find applications in the polymer industry as a monomer or in the production of sensors and semiconductors due to its chemical properties.

When handling Methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, it should be cleaned up carefully following the manufacturer's safety data sheet (SDS) guidelines. Ensure proper storage in a cool, dry place away from heat sources and incompatible materials.