Compound Q&A

How is ethyl 2-(ethoxymethylene)-3-oxo-butanoate (CAS: 3788-94-1) typically synthesized?

Answer

ethyl 2-(ethoxymethylene)-3-oxo-butanoate
Ethyl 2-(ethoxymethylene)-3-oxo-butanoate is typically synthesized by the reaction of ethyl acetoacetate with ethyl vinyl ether in the presence of a catalytic amount of an acid, such as hydrochloric acid. The reaction yields a high selectivity and good yield, making it a practical and efficient method for producing this compound.

About

CAS No 3788-94-1
English Name ethyl 2-(ethoxymethylene)-3-oxo-butanoate
Molecular Formula C9H14O4
Molecular Weight 186.21 g/mol
SMILES CCOC=C(C(=O)C)C(=O)OCC
InChIKey FNASCUBBFNCFQO-VURMDHGXSA-N
Last Updated: 2025-09-10 15:15

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