Compound Q&A

How is Benzyl (4-bromo-3-fluorophenyl)carbamate (CAS: 510729-01-8) typically synthesized?

Answer

Benzyl (4-bromo-3-fluorophenyl)carbamate
Benzyl (4-bromo-3-fluorophenyl)carbamate is typically synthesized through a multi-step process involving bromination and carbamylation. The initial step involves bromination of 3-fluoro-4-hydroxybenzylamine to form the brominated intermediate. This intermediate is then treated with benzyl chloride in the presence of a catalytic amount of base to produce the desired carbamate compound. The reaction conditions include anhydrous organic solvents and elevated temperatures to ensure high yield and selectivity.

About

English Name Benzyl (4-bromo-3-fluorophenyl)carbamate
Molecular Formula C14H11BrFNO2
Molecular Weight 324.149 g/mol
SMILES C1=CC=C(C=C1)COC(=O)NC2=CC(=C(C=C2)Br)F
InChIKey UPTMRBYILBFUPA-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15

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