Compound Q&A

How is 2,6-Di-O-methyl-β-cyclodextrin (CAS: 51166-71-3) typically synthesized?

Answer

2,6-Di-O-methyl-β-cyclodextrin
2,6-Di-O-methyl-β-cyclodextrin is typically synthesized via the etherification of β-cyclodextrin with methyl iodide in the presence of an alkali catalyst, such as potassium hydroxide. The reaction is conducted in a solvent like dimethylformamide (DMF) under mild conditions. The selectivity and yield of the reaction are high, making this method a preferred choice for industrial production.

About

CAS No 51166-71-3
English Name 2,6-Di-O-methyl-β-cyclodextrin
Molecular Formula C56H98O35
Molecular Weight 1331.37 g/mol
SMILES COCC1OC2OC3C(COC)OC(OC4C(COC)OC(OC5C(COC)OC(OC6C(COC)OC(OC7C(COC)OC(OC8C(COC)OC(OC1C(O)C2OC)C(O)C8OC)C(O)C7OC)C(O)C6OC)C(O)C5OC)C(O)C4OC)C(OC)C3O
InChIKey XUUINCAQQVCSKK-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15

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