Compound Q&A

How is ozagrel hydrochloride (CAS: 78712-43-3) typically synthesized?

Answer

Ozagrel hydrochloride
Ozagrel hydrochloride (CAS: 78712-43-3) is synthesized through the acylation of 2-(4-chlorophenyl)-N-(2-methyl-3-nitropropyl)acetamide with acetic anhydride, followed by hydrochloric acid treatment to form the hydrochloride salt. The synthesis involves the use of acetic anhydride as the acylating agent and hydrochloric acid for the salt formation. The overall process is selective and yields a high percentage of the desired product.

About

CAS No 78712-43-3
English Name Ozagrel hydrochloride
Molecular Formula C13H13ClN2O2
Molecular Weight 264.71 g/mol
SMILES C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)O.Cl
InChIKey CWKFWBJJNNPGAM-IPZCTEOASA-N
Last Updated: 2025-09-10 15:15

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