Ozagrel hydrochloride(CAS: 78712-43-3)

Ozagrel hydrochloride (CAS: 78712-43-3) is a crystalline compound with a molecular weight of approximately 331.75 g/mol. It is sparingly soluble in water and ethanol. Ozagrel hydrochloride is stable under normal conditions but may react with bases to form the free base. It is not reactive with common reagents and has a low reactivity profile.

Ozagrel hydrochloride (CAS: 78712-43-3) is synthesized through the acylation of 2-(4-chlorophenyl)-N-(2-methyl-3-nitropropyl)acetamide with acetic anhydride, followed by hydrochloric acid treatment to form the hydrochloride salt. The synthesis involves the use of acetic anhydride as the acylating agent and hydrochloric acid for the salt formation. The overall process is selective and yields a high percentage of the desired product.

Ozagrel hydrochloride (CAS: 78712-43-3) is primarily used in the pharmaceutical industry, where it serves as a thromboxane synthetase inhibitor for the treatment of thrombotic disorders. It has applications in the development of anti-platelet agents for cardiovascular diseases. Though not extensively used, it may also find applications in research for other therapeutic areas.

When handling ozagrel hydrochloride (CAS: 78712-43-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. If a spill occurs, use appropriate spill response materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.