Compound Q&A

How is 1-(2-Chloroethoxy)propane (CAS: 42149-74-6) typically synthesized?

Answer

1-(2-Chloroethoxy)propane
1-(2-Chloroethoxy)propane (CAS: 42149-74-6) is synthesized by reacting 1-chloropropane with ethylene oxide in the presence of a catalyst such as sodium hydroxide. The reaction is typically conducted at room temperature, and the yield is moderate, around 70-80%. The use of a phase transfer catalyst can enhance the reaction selectivity and yield.

About

CAS No 42149-74-6
English Name 1-(2-Chloroethoxy)propane
Molecular Formula C5H11ClO
Molecular Weight 122.595 g/mol
SMILES CCCOCCCl
InChIKey BHDSGQOSIWVMJW-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15

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