Compound Q&A
How is 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole (CAS: 832114-00-8) typically synthesized?
Answer
3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole is typically synthesized via a metal-catalyzed coupling reaction, often using Pd(0) catalysts like Pd(PPh3)4. The reaction involves the coupling of a boronic acid derivative with a 1,2-oxazole derivative under an inert atmosphere, yielding the target compound with good selectivity and up to 90% yield.
About
CAS No
832114-00-8
English Name
3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole
Molecular Formula
C11H18BNO3
Molecular Weight
223.08 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=C(ON=C2C)C
InChIKey
CVLHETBAROWASE-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
