Compound Q&A

How is 1,1,2,2-Tetrafluoro-1-(2,2,2-trifluoroethoxy)ethane (CAS: 406-78-0) typically synthesized?

Answer

1,1,2,2-Tetrafluoro-1-(2,2,2-trifluoroethoxy)ethane
1,1,2,2-Tetrafluoro-1-(2,2,2-trifluoroethoxy)ethane (CAS: 406-78-0) is synthesized via a multistep process involving fluorination reactions. Commonly, a trifluoroethanol derivative is reacted with a fluorinating agent such as N,N-dimethylformamidine or sodium bis(trimethylsilyl)amide. The reaction typically requires a catalyst and is conducted in an anhydrous solvent. The yield and selectivity can be influenced by the choice of solvent and reaction conditions.

About

CAS No 406-78-0
English Name 1,1,2,2-Tetrafluoro-1-(2,2,2-trifluoroethoxy)ethane
Molecular Formula C4H3F7O
Molecular Weight 200.05 g/mol
SMILES C(C(F)(F)F)OC(C(F)F)(F)F
InChIKey CWIFAKBLLXGZIC-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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