Compound Q&A

How is 1-Methoxy-3-methylbenzene (CAS: 100-84-5) typically synthesized?

Answer

1-Methoxy-3-methylbenzene
1-Methoxy-3-methylbenzene can be synthesized via the Friedel-Crafts acylation of 3-methylbenzene with methanol in the presence of a Lewis acid catalyst, such as aluminum trichloride (AlCl3). The reaction yields the desired product with good selectivity and moderate yield, although the exact yield depends on the reaction conditions and catalyst used.

About

CAS No 100-84-5
English Name 1-Methoxy-3-methylbenzene
Molecular Formula C8H10O
Molecular Weight 122.17 g/mol
SMILES COc1cccc(C)c1
InChIKey OSIGJGFTADMDOB-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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