Compound Q&A
How is 2-(Chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole (CAS: 723286-98-4) typically synthesized?
Answer
2-(Chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole is typically synthesized via the reaction of 5-chloromethyl-1,3,4-oxadiazole with trifluoroacetyl chloride. The reaction is performed in the presence of a base such as triethylamine. The yield is generally good, and the selectivity is high, making this a reliable method for preparing this compound.
About
CAS No
723286-98-4
English Name
2-(Chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole
Molecular Formula
C4H2ClF3N2O
Molecular Weight
186.52 g/mol
SMILES
C(C1=NN=C(O1)C(F)(F)F)Cl
InChIKey
GPXSXZGMVOSWMN-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
