Compound Q&A
How is 2-Methoxybenzoic acid (CAS: 529-75-9) typically synthesized?
Answer
2-Methoxybenzoic acid is commonly synthesized via the methylation of benzoic acid using methyl iodide and a catalytic amount of sodium hydroxide. The reaction proceeds under basic conditions, with the methyl group being introduced at the oxygen atom in the methoxy group. The yield is typically around 80-85%, and the reaction is carried out in polar aprotic solvents like dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).
About
CAS No
529-75-9
English Name
2-Methoxybenzoic acid
Molecular Formula
C8H8O3
Molecular Weight
152.15 g/mol
SMILES
COC1=CC=CC=C1C(=O)O
InChIKey
ILUJQPXNXACGAN-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
