Compound Q&A

How is 3,5-bis(Trifluoromethyl) Benzoic Acid (CAS: 725-89-3) typically synthesized?

Answer

3,5-bis(Trifluoromethyl) Benzoic Acid
3,5-bis(Trifluoromethyl) Benzoic Acid can be synthesized via a two-step process. First, trifluoromethyl chlorides are added to benzoic acid in the presence of a base like potassium carbonate. The second step involves hydrolysis of the intermediate compound to obtain the final product. This method provides good yield and selectivity, though careful handling is necessary due to the reactivity of the intermediates.

About

CAS No 725-89-3
English Name 3,5-bis(Trifluoromethyl) Benzoic Acid
Molecular Formula C9H4F6O2
Molecular Weight 258.12 g/mol
SMILES C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C(=O)O
InChIKey HVFQJWGYVXKLTE-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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