How is Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate (CAS: 16409-34-0) typically synthesized?

Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate can be synthesized through a multi-step process involving the conversion of a cholic acid derivative to the corresponding amino acetate. Commonly, this involves protecting group chemistry, followed by deprotection and amidation steps to achieve high yield and selectivity. The reaction is typically performed under mild conditions to avoid degradation of the target compound.